Johanna Dobe Professor of Cancer Immunology
Professor, Medicine (Hematology and Oncology), Microbiology-Immunology, Pathology
Bio
Dr. Zhang is the Johanna Dobe Professor of Cancer Immunology at Northwestern University, specializing in cancer immunotherapy with a dual background in immunology and molecular oncology. His research focuses on understanding how the immune system can be harnessed to develop more effective and personalized treatments for breast cancer, particularly triple-negative breast cancer. By studying neutrophils and their role in tumor promotion, Dr. Zhang seeks to uncover novel therapeutic strategies that enhance current immunotherapies. His work bridges laboratory discovery and clinical application, aiming to improve survival and quality of life for patients facing limited treatment options.
Triple-negative breast cancer (TNBC) is an aggressive and hard-to-treat form of breast cancer often resistant to current therapies. This study focuses on a novel strategy to “disarm” neutrophils—immune cells that can support tumor growth—by reducing their tumor-promoting activity. By reprogramming neutrophils to be less supportive of tumors, this approach aims to enhance the effectiveness of existing immunotherapies and improve outcomes for patients with TNBC. Targeting neutrophils in this way provides a unique and complementary method to overcome immune evasion and offers new potential avenues for treating aggressive breast cancers.
Bin Zhang, MD, PhD
Northwestern University Feinberg School of Medicine
Current
Senior Investigator
Dezheng Huo, PhD
Using Artificial Intelligence to Integrate Imaging and Genetic Markers for Personalized Breast Cancer Risk Prediction
Current
Senior Investigator
Seema Khan, MD
Optimizing Family Planning for Young Women at High Risk of Breast Cancer
Why your gift matters
Your gift helps researchers test bold ideas, generate critical data, and take the first steps toward the next major advancement in breast cancer treatment and care.Together, we can accelerate discoveries that save lives.
