Professor, Public Health Sciences
Bio
Dr. Huo is a cancer epidemiologist whose research focuses on the genetic, molecular, and environmental factors influencing breast cancer etiology, prognosis, and treatment, with particular attention to underserved populations. He leads efforts to understand the genetic architecture of breast cancer in women of African ancestry, discovering candidate genes linked to common variants and developing models to assess risk and predict chemotherapy response. Dr. Huo is committed to translating these discoveries into precision cancer prevention and treatment strategies that improve outcomes for diverse patient populations.
Breast cancer screening saves lives, but current guidelines treat all women as having the same risk, overlooking individual differences in genetics and biology. This study aims to develop precise risk prediction models by integrating genetic risk scores with artificial intelligence analysis of mammographic images. By combining these cutting-edge tools, the project seeks to guide personalized screening decisions—such as when to start and how often to screen—ultimately improving early detection and outcomes for women at highest risk. This multimodal approach represents a step toward more accurate, individualized breast cancer prevention strategies.
Dezheng Huo, PhD
University of Chicago

Current
Senior Investigator
Seema Khan, MD
Optimizing Family Planning for Young Women at High Risk of Breast Cancer


Current
Senior Investigator
Amanda L. Marzo, PhD
Reversing Resistance to Anti-Pd1 Therapy in Triple-Negative Breast Cancer
Why your gift matters
Your gift helps researchers test bold ideas, generate critical data, and take the first steps toward the next major advancement in breast cancer treatment and care.Together, we can accelerate discoveries that save lives.