2014 LSCRF Stewardship Report

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LSCRF awards seed funding for research that demonstrates the potential to improve the detection and treatment of breast cancer. These grants help researchers pursue promising ideas and novel concepts. For projects that demonstrate great potential, researchers can then pursue larger grants from organizations and governmental agencies such as the National Cancer Institute. The breast cancer leadership at Northwestern annually selects the most worthy projects. Funding to explore new ideas is essential to finding a cure for breast cancer. For every $1.00 LSCRF has awarded to breast cancer research at Northwestern, $4.00 is awarded by the National Cancer Institute and other granting agencies.

FY 2014 Research Projects


  • Circadian Control of NAD+ as New Antineoplastic Target for Breast Cancer
    Principal Investigator: Joseph Bass, MD, PhD
  • Targeting a Novel Signaling Network Against Lung Metastasis of Breast Cancer
    Principal Investigator: Hiroaki Kiyokawa, MD, PhD
  • Role of HMGCS2-Mediated Ketogenesis in Breast Epithelial-Stromal Interaction
    Principal Investigator: Jun Wang, PhD
  • Novel Activin Antagonist Therapeutics for Breast Cancer Metastasis and Cachexia
    Principal Investigator: Teresa Woodruff, PhD
  • Cytidine Deaminases, Somatic Mutations and Breast Cancer Etiology
    Principal Investigator: Susan Clare, MD, PhD
  • Phenformin, Aromatase, and Postmenopausal Breast Cancer
    Principal Investigator: Hong Zhao, MD, PhD
  • Intervention to Enhance Dietary Adherence for Breast Cancer Prevention
    Principal Investigator: Bonnie Spring, PhD
  • Epigenomic Control of Breast Cancer
    Principal Investigator: Debabrata Chakravarti, PhD
  • A Mouse Model of Breast Tumor Dormancy and Recurrence
    Principal Investigator: Chonghui Cheng, MD, PhD

FY 2014 Educational Initiatives


  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University Lynn Sage International Travel Grant for annual Lynn Sage Breast Cancer Symposium
    Leadership: William Gradishar, MD, FACP, Sharon Markman, Director of Public Affairs, RHLCCC
    For more information: Sister Cities Symposium
  • Lynn Sage Symposium: For Scholars
    William Gradishar, MD, FACP, Sharon Markman, Director of Public Affairs, RHLCCC
  • Breast Cancer Treatment Handbook, 7th Edition
    Leadership: Nora Hansen, MD LSCRF Breast Cancer Treatment Handcook The Breast Cancer Treatment Handbook is the #1 breast cancer education book given by hospitals and doctors. The handbook is used as a patient guide to find understanding and encouragement — facts are presented with hope. It covers all aspects of breast cancer— from diagnosis to recovery, using easy-to-understand language.

To donate, contact lynnsage@nmh.org or call 312-926-4274